Martin O’Neill will have to plan without James McCarthy for Monday’s first World Cup qualifier against Serbia.
The Everton and Republic of Ireland midfielder is struggling with a groin injury that will require surgery.
The injury was a factor in McCarthy failing to land a move away from Merseyside during the transfer window. With Crystal Palace and Sunderland among the clubs showing an interest in him.
The club's failure however to sign Moussa Sissoko - who opted for Tottenham after a last minute bid - gives McCarthy a lifeline at Goodison Park. Where he does not appear to be in new manager Ronald Koeman's plans.
O’Neill confirmed the injury after the 4-0 win over Oman on Wednesday night and expressed his hope that one of his key players will be back fit in a matter of weeks.