Saturday (all kick-off times 3pm unless stated)
Wolves (13) v Brentford (10)
Kick-off: 12.30pm. Venue: Molineux. On TV: Live on BT Sport 1.
Forward Hwang Hee-chan is pushing to start for Wolves, but defender Jonny (knee) and winger Pedro Neto (knee) remain long-term absentees.
Brentford midfielder Josh Dasilva is still recovering from a hip problem and defender Mads Bech Sorensen remains sidelined by a knee injury.
Last season: No Corresponding fixture
Last five league matches: Wolves L L L L W; Brentford W W D D L
Top scorers: Castelo Daniel Podence (Wolves) 1, Francisco Trincao (Wolves) 1, Romain Saiss (Wolves) 1 and Hee-Chan Hwang (Wolves) 1; Yoane Wissa (Brentford) 1, Sergi Canos (Brentford) 1, Marcus Forss (Brentford) 1, Bryan Mbeumo (Brentford) 1, Christian Norgaard (Brentford) 1 and Ivan Toney (Brentford) 1
Match odds: H 19-20 D 21-10 A 18-5
Referee: Darren England (South Yorkshire)
Liverpool (3) v Crystal Palace (11)
Venue: Anfield. On TV: Live on Premier Sport 1.
Liverpool forward Roberto Firmino’s hamstring injury keeps him out. Defender Virgil Van Dijk and forward Sadio Mane are set to return to the side after being rested for the midweek Champions League win over AC Milan.
Crystal Palace will be without left-back Jeffrey Schlupp, while winger Eberechi Eze and defender Nathan Ferguson remain on the long-term injury list.
Last season: Liverpool 2 Crystal Palace 0, Crystal Palace 0 Liverpool 7
Last five league matches: Liverpool W W W D W; Crystal Palace L L D D W
Top scorers: Mohamed Salah (Liverpool) 4; Odsonne Edouard (Crystal Palace) 5
Match odds: H 2-9 D 5-1 A 14-1
Referee: Andrew Madley (West Yorkshire)
Burnley (18) v Arsenal (16)
Venue: Turf Moor.
New signing Maxwel Cornet may have to wait again for his Burnley debut. Centre-back Nathan Collins is available but fellow new signing Connor Roberts (groin) and defender Kevin Long (leg) are not quite ready yet while midfielder Dale Stephens (ankle) is also sidelined.
Arsenal will be without midfielders Granit Xhaka (suspension) and Mohamed Elneny (hamstring), plus defender Rob Holding (knee).
Last season: Burnley 1 Arsenal 1, Arsenal 0 Burnley 1
Last five league matches: Burnley L L L D L; Arsenal W L L L W
Top scorers: Chris Wood (Burnley) 1; Pierre-Emerick Aubameyang (Arsenal) 4
Match odds: H 14-5 D 5-2 A 1-1
Referee: Anthony Taylor (Cheshire)
Man City (5) v Southampton (14)
Venue: Etihad Stadium.
Champions Manchester City are again without defenders John Stones and Aymeric Laporte (both muscular) and second-choice goalkeeper Zack Steffen (coronavirus).
Striker Shane Long (coronavirus) will be available for Southampton, but winger Theo Walcott and midfielder Stuart Armstrong are still sidelined with calf muscle issues.
Last season: Man City 5 Southampton 2, Southampton 0 Man City 1
Last five league matches: Man City W L W W W; Southampton L L D D D
Top scorers: Ferran Torres (Man City) 2, Jack Grealish (Man City) 2, Riyad Mahrez (Man City) 2 and Fernando Gabriel Jesus (Man City) 2; Mohamed Elyounoussi (Southampton) 4
Match odds: H 1-7 D 7-1 A 18-1
Referee: Jonathan Moss (County Durham)
Norwich (20) v Watford (15)
Venue: Carrow Road.
Norwich will have midfielder Jacob Sorensen (dead leg), forward Josh Sargent (hamstring) and defender Dimitris Giannoulis (back/neck) available. New signings Ozan Kabak and Mathias Normann could both be involved. Midfielder Pierre Lees-Melou (illness), centre-back Christoph Zimmermann (ankle), winger Przemyslaw Placheta (coronavirus), defender Bali Mumba (knee) and full-back Sam Byram (hamstring) are out.
Watford goalkeeper Ben Foster and defender Kiko Femenia are in full training again and in contention, but midfielder Dan Gosling and forward Joao Pedro are still building up fitness after spells on the sidelines.
Last season: No Corresponding fixture
Last five league matches: Norwich D L L L L; Watford W W L L L
Top scorers: Josh Sargent (Norwich) 4; Ismaila Sarr (Watford) 1, Emmanuel Bonaventure (Watford) 1, Ashley Fletcher (Watford) 1 and Juan Hernandez (Watford) 1
Match odds: H 23-20 D 12-5 A 12-5
Referee: Robert Jones (Merseyside)
Aston Villa (12) v Everton (4)
Kick-off: 5.30pm. Venue: Villa Park. On TV: Live on Sky Sports Main Event and Sky Sports Premier League.
Aston Villa pair Emi Buendia and Emi Martinez will be assessed when they return from Croatia following their quarantine after Argentina duty. Winger Jaden Philogene-Bidace and midfielder Carney Chukwuemeka are injured.
Everton remain without striker Dominic Calvert-Lewin (quadriceps and toe) but playmaker James Rodriguez might be involved for the first time this season.
Last season: Aston Villa 0 Everton 0, Everton 1 Aston Villa 2
Last five league matches: Aston Villa W L W D L; Everton L W D W W
Top scorers: Anwar El Ghazi (Aston Villa) 3 and Cameron Archer (Aston Villa) 3; Richarlison (Everton) 1
Match odds: H 29-20 D 11-5 A 2-1
Referee: Craig Pawson (South Yorkshire)
Sunday
Brighton (6) v Leicester (9)
Kick-off: 2pm. Venue: Amex Stadium.
Adam Webster (hamstring) will sit out for Brighton but fellow defender Dan Burn (knee) is back in contention. Enock Mwepu is available but fellow midfielder Pascal Gross is still not (both Covid-19 issues), forward Aaron Connolly (glute) is fit again and the plan is for full-back Tariq Lamptey (hamstring) to make his comeback in next Wednesday’s Carabao Cup tie against Swansea.
Leicester are expected to be without defender Jonny Evans (foot), while forward Ayoze Perez is suspended. Striker Jamie Vardy, playmaker James Maddison and midfielder Youri Tielemans are in line for a recall.
Last season: Brighton 1 Leicester 2, Leicester 3 Brighton 0
Last five league matches: Brighton L W W L W; Leicester L W L W L
Top scorers: Neal Maupay (Brighton) 2; Jamie Vardy (Leicester) 2
Match odds: H 17-10 D 11-5 A 7-4
Referee: Stuart Attwell (Warwickshire)
West Ham (8) v Man Utd (1)
Kick-off: 2pm. Venue: London Stadium. On TV: Live on Sky Sports Main Event and Sky Sports Premier League.
West Ham will be without Michail Antonio. The striker is suspended following his red card at Southampton last weekend so Jarrod Bowen could move into a central attacking role.
Edinson Cavani will miss out again for Manchester United as he continues to battle a muscle strain. The Uruguay striker could return to main first-team training next week, but will definitely miss the West Ham trip. Aaron Wan-Bissaka is free to feature as his Champions League suspension does not extend to the Premier League.
Last season: Man Utd 1 West Ham 0, West Ham 1 Man Utd 3
Last five league matches: West Ham W W W D D; Man Utd W W D W W
Top scorers: Michail Antonio (West Ham) 4; Bruno Fernandes (Man Utd) 4
Match odds: H 10-3 D 27-10 A 5-6
Referee: Martin Atkinson (West Yorkshire)
Tottenham (7) v Chelsea (2)
Kick-off: 4.30pm. Venue: Tottenham Hotspur Stadium. On TV: Live on Sky Sports Main Event and Sky Sports Premier League.
Tottenham hope to welcome back Giovani Lo Celso, Cristian Romero and Davinson Sanchez following quarantine. Winger Son Heung-min (calf) and defender Eric Dier (dead leg) are doubts, along with forwards Steven Bergwijn and Lucas Moura. Defenders Japhet Tanganga (suspended) and Ryan Sessegnon (hamstring) are out.
Midfielder N’Golo Kante (ankle) will return for Chelsea, but forward Christian Pulisic (ankle) remains sidelined.
Last season: Tottenham 0 Chelsea 1, Chelsea 0 Tottenham 0
Last five league matches: Tottenham W W W W L; Chelsea L W W D W
Top scorers: Heung-Min Son (Tottenham) 2; Romelu Lukaku (Chelsea) 4
Match odds: H 7-2 D 27-10 A 4-5
Referee: Paul Tierney (Lancashire)
