Firefighters were called to tackle a blaze at a high-rise block of flats in the early hours of Thursday morning.
Crews were called to a fire on the 13th floor of the 20-storey block in Elmira Street, Lewisham, at 4.14am.
London Fire Brigade (LFB) said about 150 people left the building before the fire brigade arrived and a sprinkler system "suppressed" the fire.
Crews from Deptford, New Cross and Lewisham were among the 58 firefighters at the scene, while police and ambulance staff were also present.
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London Fire Brigade said it received 16 calls about the blaze, which was under control by 5.23am.
The cause of the fire is under investigation, LFB added. PA