A woman has died after the car she was driving collided with another car on the N4 at Bunbrosna, three miles west of Mullingar, Co Westmeath.
The crash happened at about 9.20am on Monday morning.
The male driver and female passenger in the second car were taken to hospital.
The road is currently closed for a technical examination. Local diversions are in place.
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Gardaí are appealing for witnesses and anyone with information to contact Mullingar Garda Station on 044-9384000 The Garda Confidential Line, 1800 666111 or any Garda Station.