Eli Lilly

Expensive medicines made by Pfizer, J&J and Merck selected for talks in biggest pharma shake-up in decades

Donanemab found to slow ‘clinical decline’ by up to 35%, meaning that people with the disease could still go about performing day-to-day tasks

Project delivery specialist reported operating profits of €44m for 2022

Danish drugmaker pushing for US and EU approval but has struggled to meet demand for its Ozempic and Wegovy drugs

Energy stocks among the fallers, while Dublin’s Iseq closes lower

Shares climb after company says drug met all primary and secondary goals of the trial

Chief executive says draft plan to cut market exclusivity protection could make pursuing some treatments unviable

US firms reducing capital investment outside North America

Development to create 1,200 construction jobs, 300 new positions once operational

Ireland has moved from a position when a lot of factors were in its favour to a more mixed picture

Social media is no stranger to misinformation, but the Chief Twit has made it a defining feature in record time

Building and travel stocks struggle on Iseq

Limited efficacy means it is increasingly seen as a therapy for those who cannot take rival medications

Roche CEO warns of likely 30% reduction in demand for Covid medicines and tests this year

Company to invest €400m in manufacturing operation and will begin hiring immediately

Markets report: Cairn soars 7.2 per cent on pledge to return €95m to investors this year

Shareholder proposal demands pharma group open up Covid-19 vaccine tech to poorer countries

German researchers find therapies less effective in lab tests

Reported approval comes amid surge in infections and hospitalisations

Antiviral drug hailed by experts as an important new tool to combat pandemic

Company’s molnupiravir pill has been hailed as potential breakthrough

New antibody treatment could help prevent Covid in those with poor vaccine response

Pharmaceuticals company developing twice-daily pill for patients diagnosed with virus

New study findings account for diminished effectiveness of vaccines against variant

Market concludes Government announcement on BoI is a positive signal on capital

Treatment cuts fatalities among patients without antibodies by a fifth in trial

Phase 3 stage shows drug not significantly more effective than placebo

Many scientists opposed approval of controversial treatment, saying it did not work

Antibody treatment sales fall amid fears that new variants could prove resistant to it

Irish biopharmaceutical company stake part of package sold to Rosetta Capital

Rare black leader of a major US company, he oversaw development of cancer blockbuster Keytruda

Agenda: From tax to regulation of big tech Irish economy will be affected by White House decisions

Trial will begin in the first quarter of 2021

World round-up: India’s daily rise in cases stays below 40,000 for fourth day

Experimental antibody drug is similar to the treatment given to Donald Trump

Much of research behind vaccines has been funded by governments

Vaccines may boost profits in years ahead, but for now they are a drain on budgets

This follows losses connected with vaccine trails and US stimulus

Drug to be assessed for ability to stave off infections for up to a year in some people

Mining, drinks and tech companies among the climbers